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Introduction The oral cavity supports complex microbial communities that play a crucial role in both oral and systemic health. When this balance is disrupted, it can lead to conditions such as gingivitis and periodontitis. Certain species, particularly Porphyromonas gingivalis , act as pathogens that promote disease progression even at low abundance. Oral biofilm development follows a structured sequence, beginning with early colonizers such as Streptococcus , which alter lo
Introduction Multiomics (i.e., multiple omics; hereafter referred to as omics) is an emerging interdisciplinary approach to studying complex systems that involves integration of biological data from multiple "omics" fields. Typically including a combination (or all) of the following: genomics, epigenomics, transcriptomics, metabolomics, and proteomics. This provides a comprehensive understanding of how these systems operate at multiple scales from the molecular to whole-organ