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Prove the efficacy of your active ingredient on real skin

CLINICAL TESTING DESIGNED TO VALIDATE PERTFORMANCE

We help ingredient manufacturers generate robust, clinically relevant evidence by testing actives within controlled formulations, delivering clear insight into biological impact and optimal performance.

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Ingredient testing, designed for real-world application

Sequential evaluates active ingredients within controlled base formulations, ensuring results reflect how ingredients perform on human skin.

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We design studies to isolate and quantify ingredient impact through two core approaches:

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  • Active vs control formulations
    Assess the biological effect of an ingredient against a 
    matched base formulation.

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  • Dose-response evaluation
    Compare different concentrations of the same active to determine optimal performance and efficacy thresholds.

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By integrating biomarker profiling, microbiome analysis, and clinically relevant endpoints, we generate clear, reproducible insight into ingredient activity.

The challenge of validating ingredient performance

Demonstrating the efficacy of a novel ingredient is rarely straightforward.

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Raw actives cannot be meaningfully tested in isolation, yet many studies fail to reflect real-world use within formulations, limiting the relevance of results.

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Without a structured, comparative study design, it becomes difficult to:

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  • isolate the true impact of an ingredient

  • understand dose-response relationships

  • generate credible, claim-ready evidence

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ingredient impact

Understand the true biological effect of your active within a controlled formulation environment.

Dose-response clarity

Determine optimal concentration ranges through structured comparative study design.

Claim-ready evidence

Generate robust, biomarker-driven data to support technical documentation and commercial claims.

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