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Skin Microbiome Testing

As the skincare industry grows, consumers demand transparency from the brands formulating their products. It has become essential for formulators to create products they are willing to test to present scientifically backed data-driven evidence of their products' true effects. 

Sequential offers microbiome testing for your skincare formulations, ranging from moisturizers, serums, cleansers, SPF products, etc.

We are dedicated to understanding how your product interacts with the skin and its microbes. Depending on how in-depth you want to go, we offer qPCR, 16S, ITS, and Shotgun Metagenomics. 

Personalized Approach to Testing

Unlike other methodologies present within the industry,  Sequential's approach ensures that your product's data and analysis will stand the test of industry regulations when they are introduced. You can tailor your study entirely to your unique requirements. 

Test Products in a Real-Life Context

The microbiome comprises a complex ecosystem of microorganisms that live together in a delicate balance, which is why it's best to test directly upon it directly. To fully understand the impact a product is having on the microbiome, in vivo is the only way.

Collect Longitudinal Data

With in vivo testing we can design your study around the extended use of a product over multiple time points. This allows us to review how a product is performing before and after usage, but also take into account its gradual impact on the microbiome.

Measure Against a Control Group

Measure a product against a control group that might have a different percentage of your active ingredient within its formulation or no active at all. This will allow for deeper insights into the impact of a formulation on microbial balance and diversity. 

4 Sequencing Reports To Pick From

Depending on your development stage and what you are interested in studying we offer qPCR, 16S, ITS, and Shotgun Metagenomics. With our qPCR Smart Probes™ we can go down to the strain level in our analysis. 

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Skin Texture

The body's skin surface consists of the largest organ within the human body, hosting trillions of microbes (bacteria, viruses, fungi, etc.). These microbes protect the body from external forces, playing a key role in systemic human health. 

Clinically Validated Collection System

In addition to skin swabs, at Sequential we have developed another strong innovation to collect reliable, reproducible, and straight forward skin samples - making it that much easier to do remote consumer and clinical studies.

- Validated with external parties for DNA and RNA collection, both from microbial and host cells.
 

- Published in peer-reviewed journals, showing ease of collection and adoption for clinical studies in a range of studies.

-Clinically tested on 7 unique body sites.

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Gold Standard Certification

Sequential has developed the gold standard test for products designed to target the microbiome, in vivo (in, or on, humans). Finally, we can give some certainty about if a product is truly affecting the microbiome.

Using next-generation sequencing of the collection of micro-organisms found on the body, before and after product usage, Sequential investigates the microbial balance and diversity, and particular micro-organisms we know are important and play a role in a healthy microbiome.

We give you an in vivo certification that your product maintains the microbiome. And it’s not exclusive to skincare! We do this for haircare products, oral products, and vulva/vaginal microbiomes.

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Supplement Your Microbiome Study

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Recruitment Services

Let us take care of the entire candidate recruitment process for you!

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Biophysical Assessments

Increase your data on the use of your product by evaluating additional biophysical factors.

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Formulation Support

Seek consultation advice for your formulation if you are re-formulating or developing a new product.

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FAQ

  • What is Sequential's testing platform?
    Sequential has developed the gold standard test for microbiome-friendly products, in vivo (in, or on, humans). Finally, we can give some certainty about if a product is truly affecting the microbiome. We offer a complete end-to-end solution to support microbiome-friendly claims. From consultancy and study design to our proprietary microbiome testing kits. We analyse, interpret and report our findings to meet your needs.
  • Why is it necessary to test the microbiome in vivo?
    At present, there are no regulations for microbiome-related formulas that brands and formulators can follow, however, it has been universally acknowledged that the in vivo method of conducting clinical studies is becoming critical and paramount to getting marketing claims through. When regulations are introduced, which may be imminent, the in vitro system will find itself lacking, resulting in limited claims and certifications that do not hold their value. This is why, we at Sequential strive to offer an in vivo approach, knowing full well that we want our client's claims to be significantly backed by scientific and quantifiable data.
  • What type of sequencing technology does Sequential use for analysis?
    We offer four types of sequencing techniques including qPCR with our Smart Probes™, 16S, ITS and Shotgun Metagenomics. Using next-generation sequencing of the collection of microorganisms found on the body, during product usage, Sequential investigates the microbial diversity, and particular microorganisms we know are important and play a role in a healthy microbiome.
  • Does Sequential offer claims certification for tested products?
    We provide our clients with a certification to claim “Maintains the Microbiome” subject to in vivo testing results which can be used in communication efforts. Once your product is tested with our qPCR Smart Probes™ and has shown favourable results in supporting the microbiome, we can certify your product with our Maintains the Microbiome certification seal. We have ensured that our seal and certification are backed by quantifiable data and scientifically significant markers. The aim is to ensure our clients feel confident in making their claims and can communicate the true benefit of their microbiome formulations.
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